Atherosclerosis is the build up of plaques in blood vessel walls, composed of fats and the debris of dead cells. Blood vessels are narrowed and weakened, and eventually something important ruptures or blocks, producing a heart attack or stroke. Cholesterols circulate in the bloodstream, attached to low-density lipoprotein (LDL) particles. The immune cells known as monocytes are responsible for ensuring that excess cholesterols stuck in blood vessel walls are removed and returned to the liver to be excreted. They do this by entering blood vessel walls, transforming into macrophages, ingesting the cholesterols, and then handing them off to high-density lipoprotein (HDL) particles. In older individuals, increased inflammation and oxidative stress causes macrophages to become dysfunctional. Macrophages can be overwhelmed by large amounts of cholesterol, but From https://jamesjohnson10.blogspot.com/2019/06/progression-of-atherosclerosis-is.html From https://richardwood1.blogspot.com/2019/06/progression-of-atherosclerosis-is.html from https://richardwood1.wordpress.com/2019/06/19/progression-of-atherosclerosis-is-slowed-in-mice-via-targeting-senescent-cells/ from https://johnmurphy3.blogspot.com/2019/06/progression-of-atherosclerosis-is.html
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John Murphy
Forests at different latitudes and elevations form distinctly different ecozones: boreal forests near the poles, tropical forests near the equator and temperate forests at mid-latitudes. Higher elevation areas tend to support forests similar to those at higher latitudes, and amount of precipitation also affects forest composition. ArchivesNo Archives Categories |